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Rare Systemic Response to Titanium Spinal Fusion Implant: Case Report.


09/05/2020

A 67-year-old female with an unreported nickel allergy developed severe debilitating anorexia and fatigue one month post operatively, secondary to minimally invasive thoracic spinal fixation for T11 burst fracture with disruption of posterior elements. Over a two year period, weight loss reached approximately 25 kilograms with loss of muscle mass and subcutaneous tissue surrounding the spinal implants. The screws and rods were removed to avoid skin erosion. Upon hardware removal, the patient had rapid weight gain, improved stamina and generalized sense of well-being. We recommend the removal of spinal hardware in patients with suspected systemic titanium hypersensitivity reaction.

Case Report.

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The information on this website is not intended to, and does not, in anyway, constitute medical advice. The material is provided for information purposes only. It is based upon the Authors’ personal experiences. Please consult your qualified medical professional.